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Willows Scientific Papers for the following veterinary specialist:
Hardy JI (2017) Skin diseases affecting the nasal planum and footpads of dogs. In Practice; 39 (5): 203-213
Skin diseases that affect the nasal planum and footpads of dogs are generally quite rare but, when they do occur, the two sites are often affected together and, due to their visible location, can cause considerable concern and distress for owners. Diseases range from benign cosmetic conditions to serious and life-threatening disorders, so early recognition of a problem and an accurate diagnosis are important. This article reviews the important conditions that affect the nasal planum and footpads of dogs, giving details of their clinical signs and possible treatments.
Hardy JI, Loeffler A (2017) Diagnosis and management of MRSP in dogs and cats. Vetcpd Journal; 4 (1): 8-12
Hardy JI, Hendricks A, Loeffler A, Chang YM, Verheyen KL, Garden OA, Bond R. (2014) Food-specific serum IgE and IgG reactivity in dogs with and without skin disease: lack of correlation between laboratories. Veterinary Dermatology 25: 447-455
Despite conflicting data on their utility and no reports on interlaboratory reproducibility, serum food-specific antibodies are commonly assayed in first-opinion canine practice.
To determine both the variability of test results between two laboratories and the frequencies and magnitudes of food reactivity in dogs of different disease status.
Sera were obtained from eight dogs with cutaneous adverse food reaction (Group A), 22 with nonfood-induced atopic dermatitis (Group B), 30 with an allergic/inflammatory phenotype (Group C), 12 with miscellaneous skin diseases (Group D) and nine healthy dogs (Group E).
Paired sera were submitted to two laboratories (A and B) for assays of food-specific IgE and IgG antibodies.
Numbers of positive IgE and IgG tests determined by each laboratory in Groups A, B, D and E were comparable (Group C not included). Significant differences in the magnitude of IgE reactivity between groups for each allergen were seen only for lamb (Laboratory A, P = 0.003); lamb reactivity in Group D exceeded Group E (P = 0.004) but was comparable between all other groups. Agreement (kappa statistic) between the two laboratories’ tests was ‘moderate’ for one antigen (potato IgE), ‘fair’ for four (corn IgE, rice IgE and IgG and soya bean IgG), ‘slight’ for eight (six IgE and two IgG) and ‘less than chance’ for the remaining six antigens (three IgE and three IgG).
Conclusions and clinical importance
These laboratories’ tests appear to have dubious predictive clinical utility because they neither correlate nor distinguish between dogs of different disease status.
Hardy JI, Sinclair G, Fox MT, Loeffler A. (2012) Feline sarcoptic mange in the UK: a case report. Veterinary Record 171: 351
The burrowing mites, Sarcoptes and Notoedres, belong to the family Sarcoptidae which can cause scabies, a pruritic, contagious skin disease in animals and humans. Notoedres cati is the burrowing mite typically associated with feline scabies (Foley 1991) while Sarcoptes is associated with sarcoptic mange in dogs and humans. Notoedres mites are smaller than Sarcoptes, have ‘thumb print’-like dorsal striations, shorter limb stalks and a dorsal anus compared with the terminal anus, dorsal pegs and spines seen on Sarcoptes species (Scott and others 2001).
While information on canine sarcoptic mange is available, little is known about feline scabies. To the authors' knowledge, no cases of feline notoedric mange have been reported in the UK since the 1960s (Joyce 2010), with only sporadic reports from other parts of the world where it is considered epizootic (Delucchi and Castro 2000, Itoh and others 2004). Similarly, sarcoptic mange due to Sarcoptes scabiei in cats has only been reported infrequently worldwide. Three cases of pruritic skin disease associated with S scabiei in cats have been reported in continental Europe and North America (Bussieras 1984, Hawkins and others 1987, Kontos and others 1998), while a single case without pruritus was described in Taiwan (Huang and others 1998). Furthermore, feline scabies may also be associated with systemic disease or concurrent skin disease (Huang and …